Automated Ki-67 Quantification of Immunohistochemical Staining Image of Human Nasopharyngeal Carcinoma Xenografts
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چکیده
منابع مشابه
Automated Ki-67 Quantification of Immunohistochemical Staining Image of Human Nasopharyngeal Carcinoma Xenografts
Nasopharyngeal carcinoma is one of the malignant neoplasm with high incidence in China and south-east Asia. Ki-67 protein is strictly associated with cell proliferation and malignant degree. Cells with higher Ki-67 expression are always sensitive to chemotherapy and radiotherapy, the assessment of which is beneficial to NPC treatment. It is still challenging to automatically analyze immunohisto...
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Objective Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands. It’s rather bland histological appearance that masks its ultimate biological aggressiveness. Evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. Ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. The aim ...
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BACKGROUND Proliferative activity has been shown to be of prognostic significance for several malignancies. Ki-67, a cell cycle associated antigen, is regarded as a promising proliferation marker. Very few results on the proliferative activity of head and neck cancer and their potential prognostic value are available. MATERIALS AND METHODS The proliferative activity of 104 squamous cell carci...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep32127